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What is NIPT and when is it done? NIPT is a genetic screening test that can tell you about the genetic health risks of your pregnancy. Safe NIPT is a simple blood test that looks at DNA from the baby that is circulating in the mother’s blood. Accurate NIPT is the most accurate prenatal aneuploidy screening test available. Supported by medical professional societies That includes the American College of Obstetricians and Gynecologists, International Society of Prenatal Diagnosis, and the American College of Medical Genetics and Genomics. How does NIPT work? Your blood contains fragments of DNA known as cell-free DNA (cfDNA). During pregnancy, a woman’s blood will also contain small fragments of DNA from the baby. With a simple blood test, NIPT can noninvasively detect DNA from your baby to determine whether there is an increased or decreased risk of certain genetic conditions. What can NIPT tell us? Many parents may feel that knowing as much as possible, as early as possible, can help them be better prepared. The results of testing may help you and your family plan and discuss options with your doctor, including the need for a diagnostic test to confirm the presence of a genetic condition. What does NIPT screen for? Genetic conditions are one cause of health problems. Some genetic conditions are caused by having an extra or missing chromosome. Down syndrome Edwards syndrome Patau syndrome Sex chromosome conditions Early pregnancy: The fetal cell-free DNA in plasma is around 0.39% to 11.9% of total free DNA with an average rate 3.4%, the content is very small. Pregnancy for 12 weeks: The fetal cell-free DNA is 2.33% to 11.4% of total free DNA, with an average rate 6.2%, the content tends to be stable and increasing. Non-invasive testing requires at least 5% of fetal cell-free DNA. There is a certain proportion of pregnant women who cannot be detected because of low concentration of fetal cell-free DNA, if the protection is not good, even 0.1% of DNA releasing from white blood cells burst can make NIPT results unreliable. Dewei Cell-free DNA BCT is a good choice for NIPT! Room Temperature Storage: Store and Transport at 2-35 ℃, can be stable for 7 days after sample collection. Wide range of applications: used for NIPT （Non-invasive Prenatal Testing）, ctDNA (Circulating Tumor DNA), Cell-free DNA detection of organ transplantation, third-party medical laboratory, hospital laboratory and obstetrics, etc. Cell-Free DNA BCT protects the Cell-Free DNA in venous blood,thus effectively inhibits nuclease degradation in plasma and DNA release in nucleated cells. By Cell-Free DNA BCT, plasma isolated after centrifugation can be used for molecular diagnosis.
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